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carlberg c human epigenomics 2018

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Textbook in PDF format This book aims to summarize, in a condensed form, the role of epigenomics in defining chromatin states that are representative of active genes (euchromatin) and repressed genes (heterochromatin). Moreover, this book discusses the principles of gene regulation, chromatin stability, genomic imprinting and the reversibility of DNA methylation and histone modifications. This information should enable a better understanding of cell type identities and will provide new directions for studies of, for example, cellular reprograming, the response of chromatin to environmental signals and epigenetic therapies that can improve or restore human health. In order to facilitate the latter, we favor a high figure-to-text ratio following the rule “a picture tells more than thousand words”. Introduction What Is Epigenomics? Methods and Applications of Epigenomics Molecular Elements of Epigenomics The Structure of Chromatin DNA Methylation The Histone Code Chromatin Modifiers Chromatin Remodelers and Organizers Impact of Epigenomics in Health and Disease Embryogenesis and Cellular Differentiation Population Epigenomics and Aging Cancer Epigenomics Neuroepigenetics Epigenomics of Immune Function Nutritional Epigenomics

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Carlberg C. Molecular Immunology. How Science Works 2022.pdf 10.0 MB
Carlberg C. Human Epigenomics 2018.pdf 38.6 MB

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carlberg c human epigenomics 2018

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