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strachan t genetics genomics medicine 2ed 2023

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Textbook in PDF format The second edition of this textbook written for undergraduate students, graduate students and medical researchers, Genetics and Genomics in Medicine explains the science behind the uses of genetics and genomics in medicine today, and how it is being applied.Maintaining the features that made the first edition so popular, this second edition has been thoroughly updated in line with the latest developments in the field. DNA technologies are explained, with emphasis on the modern techniques that are revolutionizing the use of genetic information in medicine and indicating the role of genetics in common diseases. Epigenetics and non-coding RNA are covered in-depth as are genetic approaches to treatment and prevention, including pharmacogenomics, genetic testing, and personalized medicine. A dedicated chapter charts the latest insights into the molecular basis of cancers, cancer genomics and novel approaches to cancer detection. Coverage of genetic testing at the level of genes, chromosomes and genomes has been significantly expanded and updated. Extra prominence has been given to additional genomic analyses, ethical aspects, and novel therapeutic approaches. Various case studies illustrate selected clinical applications. This book is equally suited for newcomers to the field as well as for engineers and scientists that have basic knowledge in this field but are interested in obtaining more information about specific future applications. Fundamentals of DNA, Chromosomes, and Cells Fundamentals of Gene Structure, Gene Expression, and Human Genome Organization Principles Underlying Core DNA Technologies Principles of Genetic Variation Single-Gene Disorders: Inheritance Patterns, Phenotype Variability, and Allele Frequencies Principles of Gene Regulation and Epigenetics How Genetic Variation in DNA and Chromosomes Causes Disease Identifying Disease Genes and Genetic Susceptibility to Complex Disease Genetic Approaches to Treating Disease Cancer Genetics and Genomics

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Strachan T. Genetics and Genomics in Medicine 2ed 2023.pdf 16.0 MB

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strachan t genetics genomics medicine 2ed 2023

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